Nanopore-based single molecule sequencing of the D4Z4 array responsible for facioscapulohumeral muscular dystrophy

Subtelomeric macrosatellite repeats are difficult to sequence using conventional sequencing methods owing to the high similarity among repeat units and high GC content. Sequencing these repetitive regions is challenging, even with recent improvements in sequencing technologies. Among these repeats,...

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Detalles Bibliográficos
Autores principales: Mitsuhashi, Satomi, Nakagawa, So, Takahashi Ueda, Mahoko, Imanishi, Tadashi, Frith, Martin C., Mitsuhashi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665936/
https://www.ncbi.nlm.nih.gov/pubmed/29093467
http://dx.doi.org/10.1038/s41598-017-13712-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665936/
https://www.ncbi.nlm.nih.gov/pubmed/29093467
http://dx.doi.org/10.1038/s41598-017-13712-6

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