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Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering

The phosphoprotein (P) is the main and essential cofactor of the RNA polymerase (L) of non-segmented, negative‐strand RNA viruses. P positions the viral polymerase onto its nucleoprotein–RNA template and acts as a chaperone of the nucleoprotein (N), thereby preventing nonspecific encapsidation of ce...

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Detalles Bibliográficos
Autores principales: Renner, Max, Paesen, Guido C., Grison, Claire M., Granier, Sébastien, Grimes, Jonathan M., Leyrat, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665942/
https://www.ncbi.nlm.nih.gov/pubmed/29093501
http://dx.doi.org/10.1038/s41598-017-14448-z