Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation

Trisomy 21 (T21) causes Down syndrome (DS), but the mechanisms by which T21 produces the different disease spectrum observed in people with DS are unknown. We recently identified an activated interferon response associated with T21 in human cells of different origins, consistent with overexpression...

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Detalles Bibliográficos
Autores principales: Sullivan, Kelly D., Evans, Donald, Pandey, Ahwan, Hraha, Thomas H., Smith, Keith P., Markham, Neil, Rachubinski, Angela L., Wolter-Warmerdam, Kristine, Hickey, Francis, Espinosa, Joaquin M., Blumenthal, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665944/
https://www.ncbi.nlm.nih.gov/pubmed/29093484
http://dx.doi.org/10.1038/s41598-017-13858-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665944/
https://www.ncbi.nlm.nih.gov/pubmed/29093484
http://dx.doi.org/10.1038/s41598-017-13858-3

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