Therapeutic siRNA targeting endothelial KDR decreases portosystemic collateralization in portal hypertension

Development of portosystemic collateral vessels and gastroesophageal varices is responsible for the most serious clinical consequences of portal hypertension, but effective clinical therapies are limited. Here we developed and investigated the therapeutic potential of an innovative liposomally-formu...

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Detalles Bibliográficos
Autores principales: Gallego, Javier, Garcia-Pras, Ester, Mejias, Marc, Pell, Nuria, Schaeper, Ute, Fernandez, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665956/
https://www.ncbi.nlm.nih.gov/pubmed/29093528
http://dx.doi.org/10.1038/s41598-017-14818-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665956/
https://www.ncbi.nlm.nih.gov/pubmed/29093528
http://dx.doi.org/10.1038/s41598-017-14818-7

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