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Cationic starch/pDNA nanocomplexes assembly and their nanostructure changes on gene transfection efficiency

This study aims at developing biocompatible starch based gene carriers with good gene delivery and transfection efficacy. By controlling the molecular weight and aggregation behavior of spermine modified cationic starch (CS) molecules, nanocomplexes spontaneously formed through electrostatic interac...

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Detalles Bibliográficos
Autores principales: Wang, Hongwei, Li, Xiaoxi, Chen, Ling, Huang, Xiaoyi, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665959/
https://www.ncbi.nlm.nih.gov/pubmed/29093552
http://dx.doi.org/10.1038/s41598-017-14551-1