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In vivo-like 3-D model for sodium nitrite- and acrylamide-induced hepatotoxicity tests utilizing HepG2 cells entrapped in micro-hollow fibers

To address the need for a high throughput toxicity test in the modern food industry, an in vivo-like 3-D cell model was constructed in this study to provide an alternative to controversial long-term animal models and to improve the sensitivity and accuracy of the traditional monolayer model. The mod...

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Detalles Bibliográficos
Autores principales: Chu, Qiang, Zhao, Yiying, Shi, Xuer, Han, Wen, Zhang, Yanzhen, Zheng, Xiaodong, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665964/
https://www.ncbi.nlm.nih.gov/pubmed/29093461
http://dx.doi.org/10.1038/s41598-017-13147-z