Ly6C(hi) inflammatory monocytes promote susceptibility to Leishmania donovani infection

Ly6C(hi) inflammatory monocytes (iMO) are critical for host defense against toxoplasmosis and malaria but their role in leishmaniasis is unclear. In this study, we report a detrimental role of Ly6C(hi) iMOs in visceral leishmaniasis (VL) caused by Leishmania donovani. We demonstrate that Ly6C(hi) iM...

Descripción completa

Detalles Bibliográficos
Autores principales: Terrazas, Cesar, Varikuti, Sanjay, Oghumu, Steve, Steinkamp, Heidi M., Ardic, Nurittin, Kimble, Jennifer, Nakhasi, Hira, Satoskar, Abhay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665970/
https://www.ncbi.nlm.nih.gov/pubmed/29089636
http://dx.doi.org/10.1038/s41598-017-14935-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665970/
https://www.ncbi.nlm.nih.gov/pubmed/29089636
http://dx.doi.org/10.1038/s41598-017-14935-3

Ejemplares similares