Spermine oxidase promotes bile canalicular lumen formation through acrolein production

Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H(2)O(2)) and 3-aminopropanal, which is spontaneously converted to acrolein. SMOX is induced by a variety of stimuli including bacterial infection, polyamine analogues and acetaldehyde exposure. Howeve...

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Detalles Bibliográficos
Autores principales: Uemura, Takeshi, Takasaka, Tomokazu, Igarashi, Kazuei, Ikegaya, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665972/
https://www.ncbi.nlm.nih.gov/pubmed/29093526
http://dx.doi.org/10.1038/s41598-017-14929-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665972/
https://www.ncbi.nlm.nih.gov/pubmed/29093526
http://dx.doi.org/10.1038/s41598-017-14929-1

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