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A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy

We introduce the Interaction Factor (IF), a measure for quantifying the interaction of molecular clusters in super-resolution microscopy images. The IF is robust in the sense that it is independent of cluster density, and it only depends on the extent of the pair-wise interaction between different t...

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Detalles Bibliográficos
Autores principales: Bermudez-Hernandez, Keria, Keegan, Sarah, Whelan, Donna R., Reid, Dylan A., Zagelbaum, Jennifer, Yin, Yandong, Ma, Sisi, Rothenberg, Eli, Fenyö, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665986/
https://www.ncbi.nlm.nih.gov/pubmed/29093506
http://dx.doi.org/10.1038/s41598-017-14922-8