Asymmetric BMP4 signalling improves the realism of kidney organoids

We present a strategy for increasing the anatomical realism of organoids by applying asymmetric cues to mimic spatial information that is present in natural embryonic development, and demonstrate it using mouse kidney organoids. Existing methods for making kidney organoids in mice yield developing n...

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Detalles Bibliográficos
Autores principales: Mills, Christopher G., Lawrence, Melanie L., Munro, David A. D., Elhendawi, Mona, Mullins, John J., Davies, Jamie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665994/
https://www.ncbi.nlm.nih.gov/pubmed/29093551
http://dx.doi.org/10.1038/s41598-017-14809-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665994/
https://www.ncbi.nlm.nih.gov/pubmed/29093551
http://dx.doi.org/10.1038/s41598-017-14809-8

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