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Sequencing of glycosaminoglycans with potential to interrogate sequence-specific interactions

Technologies to sequence nucleic acids/proteins are widely available, but straightforward methodologies to sequence complex polysaccharides are lacking. We here put forward a strategy to sequence glycosaminoglycans, long linear polysaccharides involved in many biochemical processes. The method is ba...

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Detalles Bibliográficos
Autores principales: van Kuppevelt, Toin H., Oosterhof, Arie, Versteeg, Elly M. M., Podhumljak, Emina, van de Westerlo, Els M. A., Daamen, Willeke F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665995/
https://www.ncbi.nlm.nih.gov/pubmed/29093576
http://dx.doi.org/10.1038/s41598-017-15009-0