Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia

Exosomes, small (30–150 nm) extracellular vesicles (EVs) isolated from plasma of patients with acute myeloid leukemia (AML) carry leukemia-associated antigens and multiple inhibitory molecules. Circulating exosomes can deliver suppressive cargos to immune recipient cells, inhibiting anti-tumor activ...

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Detalles Bibliográficos
Autores principales: Hong, Chang-Sook, Sharma, Priyanka, Yerneni, Saigopalakrishna S., Simms, Patricia, Jackson, Edwin K., Whiteside, Theresa L., Boyiadzis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666018/
https://www.ncbi.nlm.nih.gov/pubmed/29089618
http://dx.doi.org/10.1038/s41598-017-14661-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666018/
https://www.ncbi.nlm.nih.gov/pubmed/29089618
http://dx.doi.org/10.1038/s41598-017-14661-w

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