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Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice

The aim of this study was to determine whether low dose doxycycline as an anti-inflammatory agent could improve glucose metabolism in diabetic animals. Therefore, doxycycline was supplemented in drinking water to 6-week-old male db/db mice for 10 weeks. Doxycycline reduced perirenal/epididymal fat,...

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Detalles Bibliográficos
Autores principales: Wang, Na, Tian, Xiong, Chen, Yu, Tan, Hui-qi, Xie, Pei-jian, Chen, Shao-jun, Fu, Yu-cai, Chen, Yi-xin, Xu, Wen-can, Wei, Chi-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666019/
https://www.ncbi.nlm.nih.gov/pubmed/29089617
http://dx.doi.org/10.1038/s41598-017-14408-7