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Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice
The aim of this study was to determine whether low dose doxycycline as an anti-inflammatory agent could improve glucose metabolism in diabetic animals. Therefore, doxycycline was supplemented in drinking water to 6-week-old male db/db mice for 10 weeks. Doxycycline reduced perirenal/epididymal fat,...
Autores principales: | Wang, Na, Tian, Xiong, Chen, Yu, Tan, Hui-qi, Xie, Pei-jian, Chen, Shao-jun, Fu, Yu-cai, Chen, Yi-xin, Xu, Wen-can, Wei, Chi-ju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666019/ https://www.ncbi.nlm.nih.gov/pubmed/29089617 http://dx.doi.org/10.1038/s41598-017-14408-7 |
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