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Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication

Viruses interact with multiple host cell factors. Some of these are required to promote viral propagation, others have roles in inhibiting infection. Here, we delineate the function of the cellular factor PHF13 (or SPOC1), a putative HIV-1 restriction factor. Early in the HIV-1 replication cycle PHF...

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Detalles Bibliográficos
Autores principales: Hofmann, Stephan, Dehn, Sandra, Businger, Ramona, Bolduan, Sebastian, Schneider, Martha, Debyser, Zeger, Brack-Werner, Ruth, Schindler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666080/
https://www.ncbi.nlm.nih.gov/pubmed/29021215
http://dx.doi.org/10.1098/rsob.170115