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Influence of GABA-B Agonist Baclofen on Capsaicin-Induced Excitation of Secondary Peristalsis in Humans

OBJECTIVES: Esophageal instillation of capsaicin enhances secondary peristalsis, but the γ-aminobutyric acid receptor type B (GABA-B) agonist baclofen inhibits secondary peristalsis. This study aimed to investigate whether baclofen could influence heartburn perception and secondary peristalsis subse...

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Detalles Bibliográficos
Autores principales: Lei, Wei-Yi, Hung, Jui-Sheng, Liu, Tso-Tsai, Yi, Chih-Hsun, Chen, Chien-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666117/
https://www.ncbi.nlm.nih.gov/pubmed/28981081
http://dx.doi.org/10.1038/ctg.2017.46