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Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria

Gram-negative bacteria are notoriously resistant to antibiotics, but the extent of the resistance varies broadly between species. We report that in significant human pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Burkholderia spp., the differences in antibiotic resistance are largely...

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Detalles Bibliográficos
Autores principales: Krishnamoorthy, Ganesh, Leus, Inga V., Weeks, Jon W., Wolloscheck, David, Rybenkov, Valentin V., Zgurskaya, Helen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666154/
https://www.ncbi.nlm.nih.gov/pubmed/29089426
http://dx.doi.org/10.1128/mBio.01172-17