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The Metallophore Staphylopine Enables Staphylococcus aureus To Compete with the Host for Zinc and Overcome Nutritional Immunity

During infection, the host sequesters essential nutrients, such as zinc, to combat invading microbes. Despite the ability of the immune effector protein calprotectin to bind zinc with subpicomolar affinity, Staphylococcus aureus is able to successfully compete with the host for zinc. However, the zi...

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Detalles Bibliográficos
Autores principales: Grim, Kyle P., San Francisco, Brian, Radin, Jana N., Brazel, Erin B., Kelliher, Jessica L., Párraga Solórzano, Paola K., Kim, Philip C., McDevitt, Christopher A., Kehl-Fie, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666155/
https://www.ncbi.nlm.nih.gov/pubmed/29089427
http://dx.doi.org/10.1128/mBio.01281-17