Cryptococcus neoformans Iron-Sulfur Protein Biogenesis Machinery Is a Novel Layer of Protection against Cu Stress

Copper (Cu) ions serve as catalytic cofactors to drive key biochemical processes, and yet Cu levels that exceed cellular homeostatic control capacity are toxic. The underlying mechanisms for Cu toxicity are poorly understood. During pulmonary infection by the fungal pathogen Cryptococcus neoformans,...

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Detalles Bibliográficos
Autores principales: Garcia-Santamarina, Sarela, Uzarska, Marta A., Festa, Richard A., Lill, Roland, Thiele, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666163/
https://www.ncbi.nlm.nih.gov/pubmed/29089435
http://dx.doi.org/10.1128/mBio.01742-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666163/
https://www.ncbi.nlm.nih.gov/pubmed/29089435
http://dx.doi.org/10.1128/mBio.01742-17

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