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Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepatoblastom...

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Detalles Bibliográficos
Autores principales: Crippa, Stefania, Ancey, Pierre‐Benoit, Vazquez, Jessica, Angelino, Paolo, Rougemont, Anne‐Laure, Guettier, Catherine, Zoete, Vincent, Delorenzi, Mauro, Michielin, Olivier, Meylan, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666308/
https://www.ncbi.nlm.nih.gov/pubmed/28923827
http://dx.doi.org/10.15252/emmm.201707814