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Src‐dependent phosphorylation of μ‐opioid receptor at Tyr(336) modulates opiate withdrawal

Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in the intracellular cAMP level and protein kinase A (PKA) activities within the neurocircuitry of addiction has been a leading hypothesis for opi...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Kibaly, Cherkaouia, Wang, Yu‐Jun, Xu, Chi, Song, Kyu Young, McGarrah, Patrick W, Loh, Horace H, Liu, Jing‐Gen, Law, Ping‐Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666313/
https://www.ncbi.nlm.nih.gov/pubmed/28818835
http://dx.doi.org/10.15252/emmm.201607324