Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease

Neonatal chronic lung disease (nCLD) affects a significant number of neonates receiving mechanical ventilation with oxygen‐rich gas (MV‐O(2)). Regardless, the primary molecular driver of the disease remains elusive. We discover significant enrichment for SNPs in the PDGF‐Rα gene in preterms with nCL...

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Detalles Bibliográficos
Autores principales: Oak, Prajakta, Pritzke, Tina, Thiel, Isabella, Koschlig, Markus, Mous, Daphne S, Windhorst, Anita, Jain, Noopur, Eickelberg, Oliver, Foerster, Kai, Schulze, Andreas, Goepel, Wolfgang, Reicherzer, Tobias, Ehrhardt, Harald, Rottier, Robbert J, Ahnert, Peter, Gortner, Ludwig, Desai, Tushar J, Hilgendorff, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666314/
https://www.ncbi.nlm.nih.gov/pubmed/28923828
http://dx.doi.org/10.15252/emmm.201607308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666314/
https://www.ncbi.nlm.nih.gov/pubmed/28923828
http://dx.doi.org/10.15252/emmm.201607308

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