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Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing
The information on candidate cancer driver alterations available from public databases is often descriptive and of limited mechanistic insight, which poses difficulties for reliable distinction between true driver and passenger events. To address this challenge, we performed in-depth analysis of who...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666318/ https://www.ncbi.nlm.nih.gov/pubmed/28692054 http://dx.doi.org/10.1038/onc.2017.215 |