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Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing

The information on candidate cancer driver alterations available from public databases is often descriptive and of limited mechanistic insight, which poses difficulties for reliable distinction between true driver and passenger events. To address this challenge, we performed in-depth analysis of who...

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Detalles Bibliográficos
Autores principales: Huskova, H, Ardin, M, Weninger, A, Vargova, K, Barrin, S, Villar, S, Olivier, M, Stopka, T, Herceg, Z, Hollstein, M, Zavadil, J, Korenjak, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666318/
https://www.ncbi.nlm.nih.gov/pubmed/28692054
http://dx.doi.org/10.1038/onc.2017.215