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Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas

Glioblastomas represent the most aggressive glioma grade and are associated with a poor patient prognosis. The current standard of care, consisting of surgery, radiation and chemotherapy, only results in a median survival of 14 months, underscoring the importance of developing effective new therapeu...

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Detalles Bibliográficos
Autores principales: Yan, D, Kowal, J, Akkari, L, Schuhmacher, A J, Huse, J T, West, B L, Joyce, J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666319/
https://www.ncbi.nlm.nih.gov/pubmed/28759044
http://dx.doi.org/10.1038/onc.2017.261