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Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas
Glioblastomas represent the most aggressive glioma grade and are associated with a poor patient prognosis. The current standard of care, consisting of surgery, radiation and chemotherapy, only results in a median survival of 14 months, underscoring the importance of developing effective new therapeu...
Autores principales: | Yan, D, Kowal, J, Akkari, L, Schuhmacher, A J, Huse, J T, West, B L, Joyce, J A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666319/ https://www.ncbi.nlm.nih.gov/pubmed/28759044 http://dx.doi.org/10.1038/onc.2017.261 |
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