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Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs

Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative metabolisms while type IIB fibers have few mitochondria and high glycolytic metabolic capacity. Peroxisome prolife...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Zhou, Ying, Wu, Wangjun, Hou, Liming, Chen, Hongxing, Zuo, Bo, Xiong, Yuanzhu, Yang, Jinzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666330/
https://www.ncbi.nlm.nih.gov/pubmed/29104506
http://dx.doi.org/10.7150/ijbs.20132