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Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs
Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative metabolisms while type IIB fibers have few mitochondria and high glycolytic metabolic capacity. Peroxisome prolife...
Autores principales: | Zhang, Lin, Zhou, Ying, Wu, Wangjun, Hou, Liming, Chen, Hongxing, Zuo, Bo, Xiong, Yuanzhu, Yang, Jinzeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666330/ https://www.ncbi.nlm.nih.gov/pubmed/29104506 http://dx.doi.org/10.7150/ijbs.20132 |
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