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Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity

Adenylate cyclase toxin (CyaA) is released in the course of B. pertussis infection in the host’s respiratory tract in order to suppress its early innate and subsequent adaptive immune defense. CD11b-expressing dendritic cells (DC), macrophages and neutrophils are professional phagocytes and key play...

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Detalles Bibliográficos
Autores principales: Fedele, Giorgio, Schiavoni, Ilaria, Adkins, Irena, Klimova, Nela, Sebo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666340/
https://www.ncbi.nlm.nih.gov/pubmed/28934122
http://dx.doi.org/10.3390/toxins9100293