Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain

The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perhaps preventing anthrax disease. To better understand the interactions of the LF-PA engagement comple...

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Detalles Bibliográficos
Autores principales: Machen, Alexandra J., Akkaladevi, Narahari, Trecazzi, Caleb, O’Neil, Pierce T., Mukherjee, Srayanta, Qi, Yifei, Dillard, Rebecca, Im, Wonpil, Gogol, Edward P., White, Tommi A., Fisher, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666345/
https://www.ncbi.nlm.nih.gov/pubmed/28937604
http://dx.doi.org/10.3390/toxins9100298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666345/
https://www.ncbi.nlm.nih.gov/pubmed/28937604
http://dx.doi.org/10.3390/toxins9100298

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