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Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain
The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perhaps preventing anthrax disease. To better understand the interactions of the LF-PA engagement comple...
Autores principales: | Machen, Alexandra J., Akkaladevi, Narahari, Trecazzi, Caleb, O’Neil, Pierce T., Mukherjee, Srayanta, Qi, Yifei, Dillard, Rebecca, Im, Wonpil, Gogol, Edward P., White, Tommi A., Fisher, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666345/ https://www.ncbi.nlm.nih.gov/pubmed/28937604 http://dx.doi.org/10.3390/toxins9100298 |
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