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Production, Characterisation and Testing of an Ovine Antitoxin against Ricin; Efficacy, Potency and Mechanisms of Action

Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and incidences of nefarious use. Despite these concerns, t...

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Detalles Bibliográficos
Autores principales: Whitfield, Sarah J. C., Griffiths, Gareth D., Jenner, Dominic C., Gwyther, Robert J., Stahl, Fiona M., Cork, Lucy J., Holley, Jane L., Green, A. Christopher, Clark, Graeme C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666376/
https://www.ncbi.nlm.nih.gov/pubmed/29057798
http://dx.doi.org/10.3390/toxins9100329