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Cholera toxin B subunit induces local curvature on lipid bilayers

The B subunit of the bacterial cholera toxin (CTxB) is responsible for the toxin binding to the cell membrane and its intracellular trafficking. CTxB binds to the monosialotetrahexosyl ganglioside at the plasma membrane of the target cell and mediates toxin internalization by endocytosis. CTxB induc...

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Detalles Bibliográficos
Autores principales: Pezeshkian, Weria, Nåbo, Lina J., Ipsen, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666388/
https://www.ncbi.nlm.nih.gov/pubmed/29123973
http://dx.doi.org/10.1002/2211-5463.12321