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Inhibition of nonenzymatic depurination of nucleic acids by polycations

DNA base depurination is one of the most common forms of DNA damage in vivo and in vitro, and the suppression of depurination is very important for versatile applications of DNA in biotechnology and medicine. In this work, it was shown that the polycations chitosan (Cho) and spermine (Spm) strongly...

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Detalles Bibliográficos
Autores principales: An, Ran, Dong, Ping, Komiyama, Makoto, Pan, Xiaoming, Liang, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666391/
https://www.ncbi.nlm.nih.gov/pubmed/29123979
http://dx.doi.org/10.1002/2211-5463.12308