Structural Principles in the Development of Cyclic Peptidic Enzyme Inhibitors

This review summarizes our studies in the development of small cyclic peptides for specifically modulating enzyme activity. Serine proteases share highly similar active sites but perform diverse physiological and pathological functions. From a phage-display peptide library, we isolated two mono-cycl...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Andreasen, Peter A., Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666521/
https://www.ncbi.nlm.nih.gov/pubmed/29104489
http://dx.doi.org/10.7150/ijbs.21597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666521/
https://www.ncbi.nlm.nih.gov/pubmed/29104489
http://dx.doi.org/10.7150/ijbs.21597

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