Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway

Mesangial cell proliferation has been identified as a mainly contributing factor to glomerulosclerosis, which is typical of diabetic nephropathy. However, the specific mechanisms and therapies remain unclear. PDK1 is a critical regulator of cell proliferation, but the specific role of PDK1 in diabet...

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Detalles Bibliográficos
Autores principales: Han, Fei, Xue, Mei, Chang, Yunpeng, Li, Xiaoyu, Yang, Yang, Sun, Bei, Chen, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666525/
https://www.ncbi.nlm.nih.gov/pubmed/29104493
http://dx.doi.org/10.7150/ijbs.20485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666525/
https://www.ncbi.nlm.nih.gov/pubmed/29104493
http://dx.doi.org/10.7150/ijbs.20485

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