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Diabetes Induces Abnormal Ovarian Function via Triggering Apoptosis of Granulosa Cells and Suppressing Ovarian Angiogenesis

Diabetes triggers abnormal ovarian follicular development and consequently leads to infertility. Here, we established a type 2 diabetes mouse model by feeding with high fat diet (HFD) for 15/20 weeks and assessed the effect of diabetes on follicular development and ovarian angiogenesis. After fed wi...

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Detalles Bibliográficos
Autores principales: Wu, Yanqing, Li, Yiyang, Liao, Xinghui, Wang, Zhengchao, Li, Rui, Zou, Shuang, Jiang, Ting, Zheng, Bingbing, Duan, Ping, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666528/
https://www.ncbi.nlm.nih.gov/pubmed/29104496
http://dx.doi.org/10.7150/ijbs.21172