Chlorpheniramine attenuates histamine-mediated aquaporin 5 downregulation in human nasal epithelial cells via suppression of NF-κB activation

Background: Aquaporin 5 (AQP5) is most likely the primary water channel in the human nasal mucosa and acts as a key tight junction protein. The signaling cascades responsible for AQP5 regulation are still works in progress. Objective: This study sought to determine the effects of histamine and chlor...

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Detalles Bibliográficos
Autores principales: Chang, Yung-Lung, Lin, Chun-Shu, Wang, Hsing-Won, Jian, Kai Ren, Liu, Shao-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666561/
https://www.ncbi.nlm.nih.gov/pubmed/29104484
http://dx.doi.org/10.7150/ijms.21573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666561/
https://www.ncbi.nlm.nih.gov/pubmed/29104484
http://dx.doi.org/10.7150/ijms.21573

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