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Dense Bicoid hubs accentuate binding along the morphogen gradient

Morphogen gradients direct the spatial patterning of developing embryos; however, the mechanisms by which these gradients are interpreted remain elusive. Here we used lattice light-sheet microscopy to perform in vivo single-molecule imaging in early Drosophila melanogaster embryos of the transcripti...

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Detalles Bibliográficos
Autores principales: Mir, Mustafa, Reimer, Armando, Haines, Jenna E., Li, Xiao-Yong, Stadler, Michael, Garcia, Hernan, Eisen, Michael B., Darzacq, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666676/
https://www.ncbi.nlm.nih.gov/pubmed/28982761
http://dx.doi.org/10.1101/gad.305078.117