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Dense Bicoid hubs accentuate binding along the morphogen gradient
Morphogen gradients direct the spatial patterning of developing embryos; however, the mechanisms by which these gradients are interpreted remain elusive. Here we used lattice light-sheet microscopy to perform in vivo single-molecule imaging in early Drosophila melanogaster embryos of the transcripti...
Autores principales: | Mir, Mustafa, Reimer, Armando, Haines, Jenna E., Li, Xiao-Yong, Stadler, Michael, Garcia, Hernan, Eisen, Michael B., Darzacq, Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666676/ https://www.ncbi.nlm.nih.gov/pubmed/28982761 http://dx.doi.org/10.1101/gad.305078.117 |
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