Viral-Cellular DNA Junctions as Molecular Markers for Assessing Intra-Tumor Heterogeneity in Cervical Cancer and for the Detection of Circulating Tumor DNA

The development of cervical cancer is frequently accompanied by the integration of human papillomaviruses (HPV) DNA into the host genome. Viral-cellular junction sequences, which arise in consequence, are highly tumor specific. By using these fragments as markers for tumor cell origin, we examined c...

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Detalles Bibliográficos
Autores principales: Carow, Katrin, Gölitz, Mandy, Wolf, Maria, Häfner, Norman, Jansen, Lars, Hoyer, Heike, Schwarz, Elisabeth, Runnebaum, Ingo B., Dürst, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666714/
https://www.ncbi.nlm.nih.gov/pubmed/28937589
http://dx.doi.org/10.3390/ijms18102032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666714/
https://www.ncbi.nlm.nih.gov/pubmed/28937589
http://dx.doi.org/10.3390/ijms18102032

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