Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells

Previous studies indicate that breast cancer cells with high aldehyde dehydrogenase (ALDH) activity and CD44 expression (ALDH(hi)CD44(+)) contribute to metastasis and therapy resistance, and that ALDH1 correlates with poor outcome in breast cancer patients. The current study hypothesized that ALDH1...

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Detalles Bibliográficos
Autores principales: Croker, Alysha K., Rodriguez-Torres, Mauricio, Xia, Ying, Pardhan, Siddika, Leong, Hon Sing, Lewis, John D., Allan, Alison L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666721/
https://www.ncbi.nlm.nih.gov/pubmed/28937653
http://dx.doi.org/10.3390/ijms18102039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666721/
https://www.ncbi.nlm.nih.gov/pubmed/28937653
http://dx.doi.org/10.3390/ijms18102039

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