Cargando…

Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells

Previous studies indicate that breast cancer cells with high aldehyde dehydrogenase (ALDH) activity and CD44 expression (ALDH(hi)CD44(+)) contribute to metastasis and therapy resistance, and that ALDH1 correlates with poor outcome in breast cancer patients. The current study hypothesized that ALDH1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Croker, Alysha K., Rodriguez-Torres, Mauricio, Xia, Ying, Pardhan, Siddika, Leong, Hon Sing, Lewis, John D., Allan, Alison L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666721/ https://www.ncbi.nlm.nih.gov/pubmed/28937653 http://dx.doi.org/10.3390/ijms18102039

Ejemplares similares

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH(High) Melanoma-Initiating Cells
por: Sarvi, Sana, et al.
Publicado: (2018)

The expression of ALDH1 in cervical carcinoma
por: Yao, Tingting, et al.
Publicado: (2011)

ALDH1A3 in CSCs
por: Sullivan, Kelly E., et al.
Publicado: (2017)

ALDH1 might influence the metastatic capability of HeLa cells
por: Yao, Tingting, et al.
Publicado: (2015)

Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis
por: Topping, Traci, et al.
Publicado: (2022)

Aldehyde dehydrogenase 1 (ALDH1) immunostaining in axillary lymph node metastases is an independent prognostic factor in ALDH1-positive breast cancer
por: Guan, Xin, et al.
Publicado: (2021)

Linking ALDH1 and retinoic acid signaling
por: Markham, Nicholas O., et al.
Publicado: (2019)

Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells
por: Gehlot, Prashasnika, et al.
Publicado: (2016)

Structure of putative tumor suppressor ALDH1L1
por: Tsybovsky, Yaroslav, et al.
Publicado: (2022)

Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells
por: Duong, Hong-Quan, et al.
Publicado: (2017)

Evaluation of ALDH1 expression in ipsilateral breast cancer recurrence
por: Shien, Tadahiko, et al.
Publicado: (2017)

The prognostic roles of ALDH1 isoenzymes in gastric cancer
por: Li, Kai, et al.
Publicado: (2016)

Upregulation of ALDH1B1 promotes tumor progression in osteosarcoma
por: Wang, Xin, et al.
Publicado: (2017)

Novel Disulfiram Derivatives as ALDH1a1-Selective Inhibitors
por: Omran, Ziad
Publicado: (2022)

Targeting ALDH1A1 to induce Necroptosis in Nasopharyngeal Carcinoma
por: Wang, Haihua, et al.
Publicado: (2022)

The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment
por: Sanders, Stephanie, et al.
Publicado: (2021)

ALDH1 Expression Correlates with Favorable Prognosis in Ovarian Cancers
por: Chang, Bin, et al.
Publicado: (2009)

Kinetic and structural analysis of human ALDH9A1
por: Končitíková, Radka, et al.
Publicado: (2019)

ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis
por: Wu, Yang, et al.
Publicado: (2022)

Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells
por: Lin, Li, et al.
Publicado: (2013)

Expression of the stem cell marker ALDH1 in BRCA1 related breast cancer
por: Heerma van Voss, Marise R., et al.
Publicado: (2011)

Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors
por: Li, Xinyan, et al.
Publicado: (2021)

Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer
por: Kim, Jin Cheon, et al.
Publicado: (2016)

Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors
por: Penumatsa, Krishna, et al.
Publicado: (2010)

Targeting cancer stem cells with ALDH1A1-based immunotherapy
por: DeLeo, Albert B.
Publicado: (2012)

ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer
por: Li, Xiao-shan, et al.
Publicado: (2014)

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer
por: Shen, Jia-Xin, et al.
Publicado: (2016)

Prognostic Implications of ALDH1 and Notch1 in Different Subtypes of Oral Cancer
por: de Freitas Filho, Silas Antonio Juvencio, et al.
Publicado: (2021)

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells
por: Liu, Xinwei, et al.
Publicado: (2016)

The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment
por: Zhang, Hong, et al.
Publicado: (2021)

Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer
por: Nozaki, Yuka, et al.
Publicado: (2017)

ALDH1A3 induces mesenchymal differentiation and serves as a predictor for survival in glioblastoma
por: Li, Guanzhang, et al.
Publicado: (2018)

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma
por: Yang, Ye, et al.
Publicado: (2014)

aldh7a1 Regulates Eye and Limb Development in Zebrafish
por: Babcock, Holly E., et al.
Publicado: (2014)

ALDH1A inhibition sensitizes colon cancer cells to chemotherapy
por: Kozovska, Z., et al.
Publicado: (2018)

ALDH1 as a prognostic marker for lymph node metastasis in OSCC
por: Götz, Carolin, et al.
Publicado: (2018)

ALDH3B1 Is an Independent Prognostic Biomarker of Lung Adenocarcinoma
por: Sun, Hongmei, et al.
Publicado: (2020)

ALDH2 variance in disease and populations
por: Chen, Che-Hong, et al.
Publicado: (2022)

Correction: Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors
por: Li, Xinyan, et al.
Publicado: (2023)

The rarity of ALDH (+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients
por: Hoang, Van T., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_pc2ms9fm817pgn97bc4mptl7ft