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APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells

Vascular calcification plays a role in the pathogenesis of atherosclerosis, diabetes, and chronic kidney disease; however, the role of apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) in inorganic phosphate (Pi)-induced vascular smooth muscle cell (VSMC) calcification remains unknown...

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Detalles Bibliográficos
Autores principales: Lee, Ki Mo, Lee, Eun Ok, Lee, Yu Ran, Joo, Hee Kyoung, Park, Myoung Soo, Kim, Cuk-Seong, Choi, Sunga, Jeong, Jin-Ok, Jeon, Byeong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666735/
https://www.ncbi.nlm.nih.gov/pubmed/28946662
http://dx.doi.org/10.3390/ijms18102053