Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol

Mitochondria play a crucial role in the cell fate; in particular, reducing the accumulation of calcium in the mitochondrial matrix offers cardioprotection. This affect is achieved by a mild depolarization of the mitochondrial membrane potential, which prevents the assembly and opening of the mitocho...

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Detalles Bibliográficos
Autores principales: Testai, Lara, Strobykina, Irina, Semenov, Victor V., Semenova, Marina, Da Pozzo, Eleonora, Martelli, Alma, Citi, Valentina, Martini, Claudia, Breschi, Maria C., Kataev, Vladimir E., Calderone, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666742/
https://www.ncbi.nlm.nih.gov/pubmed/28954424
http://dx.doi.org/10.3390/ijms18102060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666742/
https://www.ncbi.nlm.nih.gov/pubmed/28954424
http://dx.doi.org/10.3390/ijms18102060

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