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Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol
Mitochondria play a crucial role in the cell fate; in particular, reducing the accumulation of calcium in the mitochondrial matrix offers cardioprotection. This affect is achieved by a mild depolarization of the mitochondrial membrane potential, which prevents the assembly and opening of the mitocho...
Autores principales: | Testai, Lara, Strobykina, Irina, Semenov, Victor V., Semenova, Marina, Da Pozzo, Eleonora, Martelli, Alma, Citi, Valentina, Martini, Claudia, Breschi, Maria C., Kataev, Vladimir E., Calderone, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666742/ https://www.ncbi.nlm.nih.gov/pubmed/28954424 http://dx.doi.org/10.3390/ijms18102060 |
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