Fascaplysin Exerts Anti-Cancer Effects through the Downregulation of Survivin and HIF-1α and Inhibition of VEGFR2 and TRKA

Fascaplysin has been reported to exert anti-cancer effects by inhibiting cyclin-dependent kinase 4 (CDK4); however, the precise mode of action by which fascaplysin suppresses tumor growth is not clear. Here, we found that fascaplysin has stronger anti-cancer effects than other CDK4 inhibitors, inclu...

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Detalles Bibliográficos
Autores principales: Oh, Taek-In, Lee, Yoon-Mi, Nam, Taek-Jin, Ko, Young-San, Mah, Shinmee, Kim, Jinhee, Kim, Younghoon, Reddy, Rallabandi Harikrishna, Kim, Young Jun, Hong, Sungwoo, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666756/
https://www.ncbi.nlm.nih.gov/pubmed/28961193
http://dx.doi.org/10.3390/ijms18102074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666756/
https://www.ncbi.nlm.nih.gov/pubmed/28961193
http://dx.doi.org/10.3390/ijms18102074

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