PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs

Poly (ADP-ribose) polymerase 1 (PARP1), the best-studied isoform of the nuclear enzyme PARP family, plays a pivotal role in cellular biological processes, such as DNA repair, gene transcription, and so on. PARP1 has been found to be overexpressed in various carcinomas. These all indicate the clinica...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Luyao, Liang, Chao, Li, Fangfei, Guan, Daogang, Wu, Xiaoqiu, Fu, Xuekun, Lu, Aiping, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666793/
https://www.ncbi.nlm.nih.gov/pubmed/28991194
http://dx.doi.org/10.3390/ijms18102111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666793/
https://www.ncbi.nlm.nih.gov/pubmed/28991194
http://dx.doi.org/10.3390/ijms18102111

Ejemplares similares