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PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs
Poly (ADP-ribose) polymerase 1 (PARP1), the best-studied isoform of the nuclear enzyme PARP family, plays a pivotal role in cellular biological processes, such as DNA repair, gene transcription, and so on. PARP1 has been found to be overexpressed in various carcinomas. These all indicate the clinica...
Autores principales: | Wang, Luyao, Liang, Chao, Li, Fangfei, Guan, Daogang, Wu, Xiaoqiu, Fu, Xuekun, Lu, Aiping, Zhang, Ge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666793/ https://www.ncbi.nlm.nih.gov/pubmed/28991194 http://dx.doi.org/10.3390/ijms18102111 |
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