A Central Bioactive Region of LTBP-2 Stimulates the Expression of TGF-β1 in Fibroblasts via Akt and p38 Signalling Pathways

Latent transforming growth factor-β-1 binding protein-2 (LTBP-2) belongs to the LTBP-fibrillin superfamily of extracellular proteins. Unlike other LTBPs, LTBP-2 does not covalently bind transforming growth factor-β1 (TGF-β1) but appears to be implicated in the regulation of TGF-β1 bioactivity, altho...

Descripción completa

Detalles Bibliográficos
Autores principales: Sideek, Mohamed A., Smith, Joshua, Menz, Clementine, Adams, Julian R. J., Cowin, Allison J., Gibson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666796/
https://www.ncbi.nlm.nih.gov/pubmed/28991210
http://dx.doi.org/10.3390/ijms18102114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666796/
https://www.ncbi.nlm.nih.gov/pubmed/28991210
http://dx.doi.org/10.3390/ijms18102114

Ejemplares similares