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A Central Bioactive Region of LTBP-2 Stimulates the Expression of TGF-β1 in Fibroblasts via Akt and p38 Signalling Pathways

Latent transforming growth factor-β-1 binding protein-2 (LTBP-2) belongs to the LTBP-fibrillin superfamily of extracellular proteins. Unlike other LTBPs, LTBP-2 does not covalently bind transforming growth factor-β1 (TGF-β1) but appears to be implicated in the regulation of TGF-β1 bioactivity, altho...

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Detalles Bibliográficos
Autores principales:	Sideek, Mohamed A., Smith, Joshua, Menz, Clementine, Adams, Julian R. J., Cowin, Allison J., Gibson, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666796/ https://www.ncbi.nlm.nih.gov/pubmed/28991210 http://dx.doi.org/10.3390/ijms18102114

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